Hurwitz G A, Schwab M E, MacDonald A C, Driedger A A
Department of Diagnostic Radiology/Nuclear Medicine, University of Western Ontario, London, Canada.
Eur J Nucl Med. 1990;17(5):257-63. doi: 10.1007/BF00812367.
ECG gating of images with thallium 201 (201Tl) may improve the representation of myocardial perfusion by allowing isolation of the end-diastolic (ED) portion of the cardiac cycle. To characterize this phenomenon, circumferential distribution profiles for ED and conventional total-cycle images (TC) with 201Tl were analysed after summing ECG gated acquisitions; redistribution was defined as net washing of 201Tl for specific myocardial segments visualized on the left anterior oblique images. Scintigraphic data were compared with the presence of coronary stenoses in 150 patients. ED images had relatively less activity in the inferoseptal and inferoapical region than TC profiles. The ED mode of washout analysis provided more frequent confirmation of visually suggested redistribution than did the TC mode (84% incidence of net wash in for ED, 69% for TC). ED analysis showed a higher incidence of net 201Tl wash in in relation to critical circumflex and left anterior descending artery lesions, but yielded a similar overall performance to TC analysis in distinguishing patients with diseased coronary arteries from normal subjects. Thus, in selected cases, analysis of ED images could assist in confirming 201Tl redistribution.
利用201铊（201Tl）进行图像的心电图门控，通过分离心动周期的舒张末期（ED）部分，可能会改善心肌灌注的表现。为了描述这一现象，在对心电图门控采集的数据进行求和后，分析了201Tl的ED图像和传统全周期图像（TC）的圆周分布情况；再分布被定义为在左前斜位图像上可见的特定心肌节段的201Tl净洗脱。将闪烁扫描数据与150例患者冠状动脉狭窄的情况进行了比较。与TC图像相比，ED图像在下心尖和下前壁区域的活性相对较低。洗脱分析的ED模式比TC模式更频繁地证实了视觉上提示的再分布（ED净洗脱发生率为84%，TC为69%）。ED分析显示，与回旋支和左前降支严重病变相关的201Tl净洗脱发生率较高，但在区分冠心病患者和正常受试者方面，其总体表现与TC分析相似。因此，在某些情况下，分析ED图像有助于证实201Tl再分布。
