Masiuk A I, Dolgova E N
Fiziol Zh (1978). 1990 Nov-Dec;36(6):46-51.
Hydrocortisone has been studied for its effect on the bile secretion in rat under normal conditions and malfunction of hormonal induction mechanisms due to specific inhibitors of protein synthesis by actinomycin D, cycloheximide and puromycin. The character of changes in bile flow rate, observed as a response to hydrocortisone injection, depends on the intensity of transcription and translation processes in the rat liver cells.
已经研究了氢化可的松在正常条件下以及由于放线菌素D、环己酰亚胺和嘌呤霉素等蛋白质合成特异性抑制剂导致激素诱导机制功能失调时对大鼠胆汁分泌的影响。观察到的作为注射氢化可的松反应的胆汁流速变化特征取决于大鼠肝细胞中转录和翻译过程的强度。