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[氢化可的松对肝脏胆汁分泌功能的调节可能机制]

[Possible mechanism of regulation of the bile-secretory function of the liver by hydrocortisone].

作者信息

Masiuk A I, Dolgova E N

出版信息

Fiziol Zh (1978). 1990 Nov-Dec;36(6):46-51.

PMID:2083585
Abstract

Hydrocortisone has been studied for its effect on the bile secretion in rat under normal conditions and malfunction of hormonal induction mechanisms due to specific inhibitors of protein synthesis by actinomycin D, cycloheximide and puromycin. The character of changes in bile flow rate, observed as a response to hydrocortisone injection, depends on the intensity of transcription and translation processes in the rat liver cells.

摘要

已经研究了氢化可的松在正常条件下以及由于放线菌素D、环己酰亚胺和嘌呤霉素等蛋白质合成特异性抑制剂导致激素诱导机制功能失调时对大鼠胆汁分泌的影响。观察到的作为注射氢化可的松反应的胆汁流速变化特征取决于大鼠肝细胞中转录和翻译过程的强度。

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1
[Possible mechanism of regulation of the bile-secretory function of the liver by hydrocortisone].[氢化可的松对肝脏胆汁分泌功能的调节可能机制]
Fiziol Zh (1978). 1990 Nov-Dec;36(6):46-51.
2
[The hormonal regulation of bile secretion due to the activation of protein biosynthesis in the hepatocytes].[肝细胞中蛋白质生物合成激活所致胆汁分泌的激素调节]
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[Role of the protein-synthesizing system of hepatocytes in bile secretion].[肝细胞蛋白质合成系统在胆汁分泌中的作用]
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J Exp Zool. 1971 Aug;177(4):493-506. doi: 10.1002/jez.1401770410.
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Effects of cycloheximide, puromycin and actinomycin D on the spontaneous motility of isolated rat uterus.放线菌酮、嘌呤霉素和放线菌素D对离体大鼠子宫自发运动的影响。
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Effects of administration of hydrocortisone, actinomycin D and puromycin on carbamoylphosphate synthetase-I and ornithine carbamoyltransferase activities in fetal rat liver.氢化可的松、放线菌素D和嘌呤霉素给药对胎鼠肝脏中氨甲酰磷酸合成酶-I和鸟氨酸氨甲酰转移酶活性的影响。
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Hormonal and pharmacological alteration of angiotensinogen secretion from rat hepatocytes.
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