Ovsienko V V, Nikol'skiĭ I S
Fiziol Zh (1978). 1990 Nov-Dec;36(6):75-9.
It is established that incubation of the mast cells and lymphocytes in vitro in the medium 199 at 4 degrees C promotes spontaneous formationof mast cell-lymphocyte rosettes. While incubating in medium 199 at 37 degrees C a considerable part of mast cell-lymphocyte rosettes irreversibly dissociate in contrast to E-rosettes. Loss of ability to the formation of rosettes is due to the loss of the corresponding complementary structures mainly by the mast cells. The data are obtained which allow supposing participation in the process of dissociation of the shedding and capping phenomena induced by contact interaction of ++mast cells and lymphocytes.
已经确定，肥大细胞和淋巴细胞在4℃下于199培养基中体外孵育可促进肥大细胞 - 淋巴细胞玫瑰花结的自发形成。而在37℃下于199培养基中孵育时，与E - 玫瑰花结相比，相当一部分肥大细胞 - 淋巴细胞玫瑰花结会不可逆地解离。形成玫瑰花结能力的丧失主要是由于肥大细胞失去了相应的互补结构。获得的数据表明，可能有++肥大细胞与淋巴细胞的接触相互作用诱导的脱落和帽化现象参与了解离过程。
