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急性心肌梗死中二维超声心动图与血流动力学监测的比较

[Comparison of two-dimensional echocardiography and hemodynamic monitoring in acute myocardial infarct].

作者信息

Previtali M, Lanzarini L, Ferrario M, Mussini A, Tortorici M, Poli A

机构信息

Divisione di Cardiologia, IRCCS Policlinico S. Matteo, Pavia.

出版信息

G Ital Cardiol. 1990 Dec;20(12):1093-100.

PMID:2083803
Abstract

The aim of this study was to assess if in patients with acute myocardial infarction, two-dimensional echocardiographic asynergy index is correlated to hemodynamic parameters. Furthermore, we compared how reliable the 2 methods are to identify patients at a high risk of developing early left ventricular failure. Fifty-four consecutive patients (43 males, 11 females, mean age: 61 +/- 13 years with acute myocardial infarction were studied using hemodynamic monitoring and 2D-echocardiography within 24 hours from admission. The 2D-echo asynergy index, calculated on a 14-segment left ventricular model, was significantly correlated to heart rate (r = 0.49, p less than 0.001), pulmonary capillary wedge pressure (r = 0.47, p less than 0.001), systemic vascular resistance (r = 0.47, p less than 0.001), cardiac index (r = -0.46, p less than 0.001) and left ventricular stroke work index (r = -0.63, p less than 0.001). Both the asynergy index and the hemodynamic parameters were correlated to Killip clinical classification. In the sub-group of 46 patients initially classified as belonging to Killip class I or II, the patients who later developed left ventricular failure or those in whom it worsened showed a higher asynergy index and a greater impairment of left ventricular function when compared to the patients with an uncomplicated clinical course. The sensitivity of an asynergy index greater than or equal to 1 in predicting early cardiac failure was 75%, the specificity was 64%, the positive predictive value was 43% and the negative predictive value was 88%.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

本研究的目的是评估急性心肌梗死患者的二维超声心动图协同失调指数是否与血流动力学参数相关。此外,我们比较了这两种方法在识别早期发生左心室衰竭高危患者方面的可靠性。对54例连续的急性心肌梗死患者(43例男性,11例女性,平均年龄:61±13岁)在入院后24小时内进行血流动力学监测和二维超声心动图检查。基于14节段左心室模型计算的二维超声心动图协同失调指数与心率(r = 0.49,p<0.001)、肺毛细血管楔压(r = 0.47,p<0.001)、全身血管阻力(r = 0.47,p<0.001)、心脏指数(r = -0.46,p<0.001)和左心室每搏功指数(r = -0.63,p<0.001)显著相关。协同失调指数和血流动力学参数均与Killip临床分级相关。在最初分类为Killip I级或II级的46例患者亚组中,与临床过程未出现并发症的患者相比,后来发生左心室衰竭或病情恶化的患者表现出更高的协同失调指数和更严重的左心室功能损害。协同失调指数≥1预测早期心力衰竭的敏感性为75%,特异性为64%,阳性预测值为43%,阴性预测值为88%。(摘要截断于250字)

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