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基于体内和体外测量的内剂量评估移动生物检测实验室。

A mobile bioassay laboratory for the assessment of internal doses based on in vivo and in vitro measurements.

机构信息

Instituto de Radioproteção e Dosimetria-CNEN, Av Salvador Allende s/n - Rio de Janeiro, RJ-22780-160, Brazil.

出版信息

Health Phys. 2010 Oct;99(4):449-52. doi: 10.1097/HP.0b013e3181c03e41.

Abstract

Internal exposures may occur in nuclear power plants, radioisotope production, and in medicine and research laboratories. Such practices require quick response in case of accidents of a wide range of magnitudes. This work presents the design and calibration of a mobile laboratory for the assessment of accidents involving workers and the population as well as for routine monitoring. The system was set up in a truck with internal dimensions of 3.30 m × 1.60 m × 1.70 m and can identify photon emitters in the energy range of 100-3,000 keV in the whole body, organs, and in urine. A thyroid monitor consisting of a lead-collimated NaI(Tl)3" × 3" (7.62 × 7.62 cm) detector was calibrated with a neck-thyroid phantom developed at the IRD (Instituto de Radioproteção e Dosimetria). Whole body measurements were performed with a NaI(Tl)8" × 4" (20.32 × 10.16 cm) detector calibrated with a plastic-bottle phantom. Urine samples were measured with another NaI(Tl) 3" × 3" (7.62 × 7.62 cm) detector set up in a steel support. Standard solutions were provided by the National Laboratory for Metrology of Ionizing Radiation of the IRD. Urine measurements are based on a calibration of efficiency vs. energy for standard volumes. Detection limits were converted to minimum committed effective doses for the radionuclides of interest using standard biokinetic and dosimetric models in order to evaluate the applicability and limitations of the system. Sensitivities for high-energy activation and fission products show that the system is suitable for use in emergency and routine monitoring of individuals under risk of internal exposure by such radionuclides.

摘要

内部照射可能发生在核电站、放射性同位素生产以及医学和研究实验室中。这些实践需要在各种规模的事故发生时做出快速反应。本工作介绍了一个移动实验室的设计和校准,该实验室用于评估涉及工人和公众的事故以及常规监测。该系统安装在一辆卡车中,内部尺寸为 3.30 m × 1.60 m × 1.70 m,可在全身、器官和尿液中识别能量范围为 100-3000 keV 的光子发射体。一个由 lead-collimated NaI(Tl)3" × 3" (7.62 × 7.62 cm) 探测器组成的甲状腺监测器,使用在 IRD (Instituto de Radioproteção e Dosimetria) 开发的颈甲状腺模型进行校准。全身测量使用经塑料瓶模型校准的 NaI(Tl)8" × 4" (20.32 × 10.16 cm) 探测器进行。尿液样本使用另一个安装在钢支架上的 NaI(Tl) 3" × 3" (7.62 × 7.62 cm) 探测器进行测量。标准溶液由 IRD 的国家电离辐射计量实验室提供。尿液测量基于标准体积的效率与能量的校准。使用标准的生物动力学和剂量学模型,将检测限转换为感兴趣放射性核素的最小承诺有效剂量,以评估系统的适用性和局限性。对于高能激活和裂变产物的灵敏度表明,该系统适用于对这些放射性核素内部照射风险下的个体进行应急和常规监测。

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