Department of Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Clin Nucl Med. 2010 Oct;35(10):806-7. doi: 10.1097/RLU.0b013e3181ef0a9e.
The association between breast carcinoma and meningioma is a well-recognized phenomenon that may have important clinical implications, particularly in intracranial lesions. We report 2 cases of intracranial meningioma in adult women with a history of breast cancer, who were imaged with positron emission tomography/computed tomography (PET/CT) for evaluation of possible bone metastases. Whole-body F-18 fluoride PET demonstrated an intense intracranial focal radiotracer accumulation in both patients. Simultaneous CT showed a corresponding calcified space-occupying lesion, consistent with meningioma. Early and correct diagnosis of synchronous meningioma in F-18 fluoride bone scans might prevent relevant neurologic comorbidity.
乳腺癌与脑膜瘤之间的关联是一种公认的现象，可能具有重要的临床意义，特别是在颅内病变中。我们报告了 2 例成年女性颅内脑膜瘤的病例，她们因乳腺癌病史而行正电子发射断层扫描/计算机断层扫描（PET/CT）检查以评估可能的骨转移。全身 F-18 氟化物 PET 显示在这 2 名患者中均有强烈的颅内局灶性放射性示踪剂积聚。同时的 CT 显示出相应的钙化占位性病变，符合脑膜瘤的表现。在 F-18 氟化物骨扫描中早期和正确诊断同步脑膜瘤可以预防相关的神经并发症。
