Galldiks Norbert, Albert Nathalie L, Wollring Michael, Werner Jan-Michael, Lohmann Philipp, Villanueva-Meyer Javier E, Fink Gereon R, Langen Karl-Josef, Tonn Joerg-Christian
Department of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Institute of Neuroscience and Medicine (INM-3, -4), Research Center Juelich, Juelich, Germany.
Neurooncol Adv. 2023 Jun 3;5(Suppl 1):i84-i93. doi: 10.1093/noajnl/vdac113. eCollection 2023 May.
In patients with meningioma, diagnosis and treatment planning are predominantly based on anatomical imaging using MRI or CT. Constraints of these imaging modalities include precise meningioma delineation-especially at the skull base, in the case of -osseus growth, and in tumors with complex geometry-and the differentiation of post-therapeutic reactive changes from meningioma relapse. Advanced metabolic imaging using PET may help to characterize specific metabolic and cellular features providing additional information beyond the information derived from anatomical imaging alone. Accordingly, the use of PET in meningioma patients is steadily increasing. This review summarizes recent advances in PET imaging helpful for improving the clinical management of patients with meningioma.
对于脑膜瘤患者,诊断和治疗计划主要基于使用MRI或CT的解剖成像。这些成像方式的局限性包括精确勾勒脑膜瘤——特别是在颅底、存在骨生长的情况下以及具有复杂几何形状的肿瘤中——以及区分治疗后反应性改变与脑膜瘤复发。使用PET的先进代谢成像可能有助于表征特定的代谢和细胞特征,提供超出仅从解剖成像获得的信息之外的额外信息。因此,PET在脑膜瘤患者中的应用正在稳步增加。本综述总结了PET成像的最新进展,这些进展有助于改善脑膜瘤患者的临床管理。