来自四方棱柱木根的蒽醌类化合物。

Anthraquinones from the roots of Prismatomeris tetrandra.

作者信息

Zhang Cun-Li, Guan Hua, Xi Peng-Zhou, Deng Tao, Gao Jin-Ming

机构信息

College of Life Science, Northwest A & F University, Yangling, Shaanxi 712100, China.

出版信息

Nat Prod Commun. 2010 Aug;5(8):1251-2.

PMID:20839629

Abstract

A new anthraquinone compound, 1,3-dihydroxy-6-methoxy-2-methoxymethyl-9,10-anthraquinone (1), along with four known analogues (2-5) were isolated from the roots of Prismatomeris tetrandra. Their structures were elucidated on the basis of spectroscopic analysis. Among these compounds, lucidin omega-methyl ether (4) and lucidin omega-ethyl ether (5) were isolated from this genus for the first time. Compound 1 showed weak cytotoxic activity against A549 and LAC cell lines.

摘要

从海南虎刺的根部分离得到一个新的蒽醌类化合物1,3 - 二羟基 - 6 - 甲氧基 - 2 - 甲氧基甲基 - 9,10 - 蒽醌（1），以及四个已知类似物（2 - 5）。通过光谱分析确定了它们的结构。其中，光泽汀ω - 甲基醚（4）和光泽汀ω - 乙基醚（5）是首次从该属植物中分离得到。化合物1对A549和LAC细胞系显示出较弱的细胞毒活性。