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Quantitative MRI in isotropic spatial resolution for forensic soft tissue documentation. Why and how?

作者信息

Jackowski Christian, Warntjes Marcel J B, Kihlberg Johan, Berge Johan, Thali Michael J, Persson Anders

机构信息

Center for Medical Image Science and Visualization (CMIV), University Hospital, University of Linköping, SE-58185 Linköping, Sweden.

出版信息

J Forensic Sci. 2011 Jan;56(1):208-15. doi: 10.1111/j.1556-4029.2010.01547.x. Epub 2010 Sep 14.

DOI:10.1111/j.1556-4029.2010.01547.x
PMID:20840290
Abstract

A quantification of T1, T2, and PD in high isotropic resolution was performed on corpses. Isotropic and quantified postmortem magnetic resonance (IQpmMR) enables sophisticated 3D postprocessing, such as reformatting and volume rendering. The body tissues can be characterized by the combination of these three values. The values of T1, T2, and PD were given as coordinates in a T1-T2-PD space where similar tissue voxels formed clusters. Implementing in a volume rendering software enabled color encoding of specific tissues and pathologies in 3D models of the corpse similar to computed tomography, but with distinctively more powerful soft tissue discrimination. From IQpmMR data, any image plane at any contrast weighting may be calculated or 3D color-encoded volume rendering may be carried out. The introduced approach will enable future computer-aided diagnosis that, e.g., checks corpses for a hemorrhage distribution based on the knowledge of its T1-T2-PD vector behavior in a high spatial resolution.

摘要

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