Cortes Edmi, Cubano Antonio, Lewis John E, Castellanos Daniel
The Mental Health Hospital Center, Jackson Health System, 1695 NW 9th Avenue, Miami, FL 33136, USA.
J Forensic Sci. 2011 Jan;56(1):155-60. doi: 10.1111/j.1556-4029.2010.01541.x. Epub 2010 Sep 14.
Controversy has surrounded the use of antidepressants and suicidal behaviors in youth. This study reviewed the Medical Examiner's Office records of 253 persons aged 24 years or younger classified as suicides in Miami-Dade County, Florida, from 1990 to 2007. Information was collected regarding demographic information, suicidal characteristics, psychiatric and psychosocial factors, and toxicology results. Eighty-five percent of the sample was men, and 53.4% of the subjects were Hispanic. Consistent with previous literature, the existence of antidepressants at autopsy was rare; present in only 6% (n=15) of the victims. The occurrence of antidepressants was not significantly different between Hispanics (n=7) and non-Hispanics (n=8). The incidence of antidepressants was weakly correlated with a tendency to be men and no history of psychiatric illness. The presence of antidepressants in Hispanic youth suicide victims was similar to non-Hispanics.
抗抑郁药在青少年中的使用与自杀行为一直存在争议。本研究回顾了1990年至2007年佛罗里达州迈阿密-戴德县253名24岁及以下被归类为自杀者的法医办公室记录。收集了有关人口统计学信息、自杀特征、精神和心理社会因素以及毒理学结果的信息。样本中85%为男性，53.4%的受试者为西班牙裔。与先前的文献一致，尸检时发现抗抑郁药的情况很少见；仅在6%（n = 15）的受害者中发现。西班牙裔（n = 7）和非西班牙裔（n = 8）之间抗抑郁药的出现情况没有显著差异。抗抑郁药的发生率与男性倾向和无精神疾病史呈弱相关。西班牙裔青少年自杀受害者中抗抑郁药的存在情况与非西班牙裔相似。
