Robertz-Vaupel G M, Glasmacher A G, Vogel J, Vaupel H A, Köster O, Pizzulli L
Medizinische Universitätsklinik Bonn.
Klin Wochenschr. 1990 Nov 9;68(21):1076-81. doi: 10.1007/BF01649310.
A 64-year-old man with high malignant B-cell lymphoma in both adrenal glands was investigated. Adrenal insufficiency was his predominant symptom at presentation. Despite surgical resection of the malignancy and cytostatic chemotherapy leptomeningeal involvement occurred and the patient died nine month after the diagnosis. Nine so far reported cases with primary adrenal lymphoma were reviewed. One of these also developed lymphomatous leptomeningitis. Suggestions of a pathogenetic contribution of adrenal lymphoma to leptomeningeal involvement and arising therapeutic consequences in the treatment of primary adrenal lymphoma are discussed.
对一名患有双侧肾上腺高度恶性B细胞淋巴瘤的64岁男性进行了调查。肾上腺功能不全是其就诊时的主要症状。尽管对恶性肿瘤进行了手术切除并进行了细胞抑制化疗，但仍发生了软脑膜受累，患者在诊断后九个月死亡。对迄今报道的9例原发性肾上腺淋巴瘤病例进行了回顾。其中1例也发生了淋巴瘤性软脑膜炎。讨论了肾上腺淋巴瘤对软脑膜受累的发病机制贡献以及原发性肾上腺淋巴瘤治疗中产生的治疗后果。
