[Antibiotics as proteolysis inhibitors in the stomach].

The study was made of antibiotics action on hydrolysis of coagulated protein in gastric juice. It was established that antibiotics can produce inhibition of protein proteolysis in gastric juice. The highest antiprotease activity was reported for cephalosporins , rifampicin and penicillins, the lowest for tetracycline++. Antiprotease activity of antibiotics should be taken into consideration when defining their therapeutic effect in peptic ulcer.