理解免疫突触的结构和功能。
Understanding the structure and function of the immunological synapse.
机构信息
Program in Molecular Pathogenesis, Skirball Institute of Biomolecular Medicine and Department of Pathology, New York University, New York, New York 10016, USA.
出版信息
Cold Spring Harb Perspect Biol. 2010 Oct;2(10):a002311. doi: 10.1101/cshperspect.a002311. Epub 2010 Sep 15.
Abstract
The immunological synapse has been an area of very active scientific interest over the last decade. Surprisingly, much about the synapse remains unknown or is controversial. Here we review some of these current issues in the field: how the synapse is defined, its potential role in T-cell function, and our current understanding about how the synapse is formed.
摘要
免疫突触是过去十年中非常活跃的科学研究领域。令人惊讶的是，突触的许多方面仍然未知或存在争议。在这里，我们回顾了该领域的一些当前问题：突触的定义、它在 T 细胞功能中的潜在作用，以及我们目前对突触形成方式的理解。
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