Regulation of the Apaf-1-caspase-9 apoptosome.
作者信息
Bratton Shawn B, Salvesen Guy S
机构信息
Division of Pharmacology and Toxicology, College of Pharmacy, and Center for Molecular and Cellular Toxicology, and Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712-0125, USA.
出版信息
J Cell Sci. 2010 Oct 1;123(Pt 19):3209-14. doi: 10.1242/jcs.073643.
Abstract
摘要
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本文引用的文献
1
Structure of an apoptosome-procaspase-9 CARD complex.凋亡体- procaspase-9 CARD 复合物的结构。
Structure. 2010 May 12;18(5):571-83. doi: 10.1016/j.str.2010.04.001.
2
Crystal structure of the Caenorhabditis elegans apoptosome reveals an octameric assembly of CED-4.秀丽隐杆线虫凋亡体的晶体结构揭示了 CED-4 的八聚体组装。
Cell. 2010 Apr 30;141(3):446-57. doi: 10.1016/j.cell.2010.03.017.
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tRNA binds to cytochrome c and inhibits caspase activation.tRNA 与细胞色素 c 结合并抑制半胱天冬酶的激活。
Mol Cell. 2010 Mar 12;37(5):668-78. doi: 10.1016/j.molcel.2010.01.023.
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p38alpha- and DYRK1A-dependent phosphorylation of caspase-9 at an inhibitory site in response to hyperosmotic stress.在高渗应激反应中，p38α和DYRK1A依赖的半胱天冬酶-9在一个抑制位点的磷酸化作用。
Cell Signal. 2009 Nov;21(11):1626-33. doi: 10.1016/j.cellsig.2009.06.009. Epub 2009 Jul 5.
5
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6
Control of mitochondrial apoptosis by the Bcl-2 family.Bcl-2家族对线粒体凋亡的调控
J Cell Sci. 2009 Feb 15;122(Pt 4):437-41. doi: 10.1242/jcs.031682.
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The Jekyll and Hyde functions of caspases.半胱天冬酶的双重功能。
Dev Cell. 2009 Jan;16(1):21-34. doi: 10.1016/j.devcel.2008.12.012.
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DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine.DYRK1A在一个抑制位点使半胱天冬酶9磷酸化，并且在人细胞中被 harmine 强烈抑制。
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