Department of Pediatrics, Children's Hospital, Faculty of Medicine, Transilvania University, Brasov, Romania.
Pediatr Infect Dis J. 2011 Jan;30(1):76-8. doi: 10.1097/INF.0b013e3181f42bb6.
We report high colonization rates among 400 healthy infants and children, and moderate (66%) coverage by PCV7 and PCV10, with a superior (80%) PCV13 coverage. Most frequent serotypes were 23F, 6B, 19F, and 14. Resistance to penicillin, ceftriaxone, erythromycin, and trimethoprim/sulfamethoxazole was 83%, 18%, 62%, and 66%, respectively. 67% isolates were multidrug resistant. Pneumococcal conjugate vaccines covered 80% to 93% of multidrug resistant isolates.
我们报告了在 400 名健康婴儿和儿童中高定植率，以及 PCV7 和 PCV10 的适度（66%）覆盖率，PCV13 的覆盖率更高（80%）。最常见的血清型是 23F、6B、19F 和 14。对青霉素、头孢曲松、红霉素和甲氧苄啶/磺胺甲恶唑的耐药率分别为 83%、18%、62%和 66%。67%的分离株为多药耐药。肺炎球菌结合疫苗覆盖了 80%至 93%的多药耐药分离株。
