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[流感病毒在低温下复制适应性的研究。I.生物学特性]

[Studies of adaptation of influenza viruses to their replication in low temperature. I. Biological properties].

作者信息

Brydak L

机构信息

Zakład Wirusologii PZH w Warszawie.

出版信息

Med Dosw Mikrobiol. 1990;42(3-4):122-30.

PMID:2084448
Abstract

Influenza A/H3N2/ virus strains derived from various isolations and replicated in lowered temperatures (37 degrees, 35 degrees, 33 degrees, 30 degrees) in chicken embryos were used for the study. An alteration of temperature optimum of neuraminidase activity was established after 12-15 passages of influenza virus in lowered replication temperature and it differed depending on tested strain. During adaptation process of viruses to lowered replication temperatures no correlation between neuraminidase activity and haemagglutinating titer was seen.

摘要

来自不同分离株并在鸡胚中于较低温度（37度、35度、33度、30度）下复制的甲型H3N2流感病毒株用于该研究。流感病毒在较低复制温度下传代12 - 15次后，确定了神经氨酸酶活性最佳温度的改变，且该改变因测试毒株而异。在病毒适应较低复制温度的过程中，未观察到神经氨酸酶活性与血凝滴度之间的相关性。

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