Karyağar Savaş, Karatepe Oğuzhan, Bender Omer, Mulazımoğlu Mehmet, Ozpaçaci Tevfik, Uyanık Ercan, Karyağar Sevda S, Yalçın Orhan, Ozdenkaya Yaşar
Department of Nuclear Medicine, Istanbul, T.C.S.B. Okmeydani Training and Research Hospital, Turkey.
Indian J Nucl Med. 2010 Jan;25(1):12-5. doi: 10.4103/0972-3919.63593.
The purpose of this study is to investigate whether or not radio-guided surgery has any beneficial effects on completion thyroidectomy (CT) and the associated complication rates.
Twenty-seven patients were scheduled for CT, for thyroid carcinoma, from December 2004 to June 2005, and were included in the study. All the patients had had initial thyroid surgery in other centers and been referred to our clinic for CT. Operation findings and the effectiveness of Tc-99m radio-guided CT were analyzed.
The intraoperative mean ratio of thyroid activity to background activity counted with a gamma probe was 1.3 ± 0.3. Average operation timing was 74 ± 9 minutes. Postoperatively, no residual tissue was detected in any of the patients with ultrasonography and thyroid scintigraphy. In the first postoperative month, serum TSH level was 61 ± 16.4 mIU / L, when preoperatively it was 7.3 ± 3.1 mIU / L (P < 0.001). In the postoperative period, one patient experienced temporary hypoparathyroidism (3.9%). Permanent hypoparathyroidism or recurrent laryngeal nerve damage was not detected in any patient.
Tc-99 radio-guided CT is a reliable surgical method, which provides the detection and removal of residual thyroid tissues with minimal complications.
本研究旨在调查放射性引导手术对甲状腺全切术（CT）及相关并发症发生率是否有任何有益影响。
2004年12月至2005年6月期间，27例因甲状腺癌计划接受CT手术的患者被纳入本研究。所有患者均在其他中心接受过初次甲状腺手术，并被转诊至我院进行CT手术。分析手术结果及Tc-99m放射性引导CT的有效性。
术中用γ探测器测得的甲状腺活性与本底活性的平均比值为1.3±0.3。平均手术时间为74±9分钟。术后，超声检查和甲状腺闪烁显像未在任何患者中检测到残留组织。术后第一个月，血清促甲状腺激素（TSH）水平为61±16.4 mIU/L，术前为7.3±3.1 mIU/L（P<0.001）。术后期间，1例患者发生暂时性甲状旁腺功能减退（3.9%）。未在任何患者中检测到永久性甲状旁腺功能减退或喉返神经损伤。
Tc-99放射性引导CT是一种可靠的手术方法，能以最小的并发症检测并切除残留甲状腺组织。
