de Tullio Damiano, Rossi Camilla, Bolzon Stefano, Scagliarini Lucia, Occhionorelli Savino
Istituto di Chirurgia Generale e Toracica, Università degli Studi di Ferrara, Azienda Ospedaliero-Universitaria Arcispedale Sant'Anna, Ferrara, Italy,
Updates Surg. 2010 Oct;62(2):83-7. doi: 10.1007/s13304-010-0019-6. Epub 2010 Sep 9.
Accurate assessment and timely interventions are critical in the treatment of patients affected with necrotizing fasciitis, a rare, fulminating, potentially life-threatening, infectious process of the soft tissues. Understanding the natural history and unique characteristics of this disease is crucial to achieve early recognition, effective management and a favorable patient outcome. Classic symptoms include severe pain, erythema, mottling, crepitus, skin anesthesia, warmth, tenderness, bullous formations and edema in the affected area and fever. This article aims at reviewing the information known about this disease, collected from various sources. Radical surgical debridement, broad-spectrum antibiotics, negative pressure wound therapy and hyperbaric oxygen therapy are considered to be the cornerstones of treatment.
准确评估和及时干预对于治疗坏死性筋膜炎患者至关重要，坏死性筋膜炎是一种罕见的、暴发性的、可能危及生命的软组织感染性疾病。了解这种疾病的自然病程和独特特征对于早期识别、有效管理以及患者获得良好预后至关重要。典型症状包括严重疼痛、红斑、斑纹、捻发音、皮肤麻木、发热、压痛、水疱形成以及受累区域的水肿和发热。本文旨在综述从各种来源收集到的有关这种疾病的已知信息。根治性手术清创、广谱抗生素、负压伤口治疗和高压氧治疗被认为是治疗的基石。
