Department of Psychology, Southern Methodist University, Dallas, TX 75205, USA.
J Psychosom Res. 2010 Oct;69(4):341-51. doi: 10.1016/j.jpsychores.2010.05.004. Epub 2010 Jun 23.
Previous asthma diary studies have yielded equivocal findings on concurrent associations between lung function and mood, and prospective associations have rarely been explored. We therefore examined concurrent and prospective associations between daily mood, shortness of breath, and lung function, and studied between-individual variability and stability of concurrent associations across different times of the day.
Twenty asthma patients and 20 healthy controls recorded their positive and negative mood, shortness of breath, physical activity, peak expiratory flow (PEF) and forced expiratory volume in the first second (FEV(1)) using an electronic pocket spirometer with diary functions three times per day for about 21 days.
For both groups, PEF showed positive concurrent associations with ratings of various mood states, whereas FEV(1) was only associated with positive mood. Both indices correlated negatively with shortness of breath. Within-individual concurrent associations varied significantly in both groups and their stability varied across time of the day, with overall higher stability for associations with shortness of breath in asthma and PEF for both groups. Prospectively, higher shortness of breath consistently predicted lower lung function later during the day and on the subsequent day.
The relationship between normal mood variations and lung function is highly variable across individuals and times of the day, limiting the predictive value of average group associations. Shortness of breath is predictive of future lung function decline in asthma. Future longitudinal research should focus on extreme emotional states, effort-independent measures of lung function, and additional indicators of asthma control.
既往哮喘日记研究对肺功能和情绪之间的并发关联得出了相互矛盾的结果，前瞻性关联则很少被探索。因此，我们检验了日间情绪、呼吸急促和肺功能之间的并发和前瞻性关联，并研究了不同时间点的日间关联的个体间变异性和稳定性。
20 名哮喘患者和 20 名健康对照者使用具有日记功能的电子掌上型肺量计，每天记录 3 次，大约 21 天，记录他们的正性和负性情绪、呼吸急促、体力活动、呼气峰流速（PEF）和第一秒用力呼气量（FEV1）。
对于两组，PEF 与各种情绪状态的评分均呈正性并发关联，而 FEV1 仅与正性情绪相关。两个指数均与呼吸急促呈负相关。两组的个体内日间并发关联差异显著，其稳定性在一天中的不同时间也不同，与哮喘的呼吸急促和两组的 PEF 相关的关联总体上具有更高的稳定性。前瞻性地，较高的呼吸急促始终预示着当天晚些时候和次日肺功能的下降。
正常情绪变化与肺功能之间的关系在个体和日间时间上具有高度变异性，限制了平均组关联的预测价值。呼吸急促是哮喘患者未来肺功能下降的预测指标。未来的纵向研究应集中在极端情绪状态、与努力无关的肺功能测量指标以及哮喘控制的其他指标上。
