Flinders Medical Centre, Bedford Park, Adelaide, Australia.
J Am Acad Dermatol. 2010 Oct;63(4):642-6. doi: 10.1016/j.jaad.2009.11.586.
Actinic cheilitis is a common condition with the potential to develop into squamous cell carcinoma. Current treatments have varying cure rates and complications. The role of the erbium:yttrium-aluminum-garnet (Er:YAG) laser in the treatment of actinic cheilitis has not been widely published, despite offering theoretical advantages over current treatment modalities.
To evaluate the outcome of a series of patients treated with the Er:YAG laser for actinic cheilitis.
This was a retrospective, interventional, nonrandomized, sequential case series set in a tertiary referral, dermatologic surgery unit. Ninety-nine consecutive patients with actinic cheilitis treated with the Er:YAG laser between January 2001 and June 2008 underwent a case note review, of which 77 went on to a structured telephone interview. The main outcome measures were a subjective improvement in lip symptoms related to actinic cheilitis and objective improvement in the lips at routine follow-up.
Mean time to interview follow-up was 65.7 months. Of those interviewed, 92.2% believed there had been an improvement in the cosmetic appearance of their lips; one hundred percent believed the function of their lips had improved or remained unchanged; and 84.8% remained completely disease free at the time of follow-up. The majority of patients (93.5%) were satisfied with the laser treatment. Scarring as a direct result of the laser occurred in 5.1% of patients.
Retrospective nature of data collection; inability to interview all patients who underwent treatment.
The Er:YAG laser is a successful modality for the treatment of actinic cheilitis with good functional and cosmetic results and only a small risk of long-term scarring. It should be considered as a first-line treatment for the disease.
光化性唇炎是一种常见的疾病,有发展为鳞状细胞癌的潜在风险。目前的治疗方法治愈率和并发症发生率各不相同。尽管铒:钇铝石榴石(Er:YAG)激光在治疗光化性唇炎方面具有理论优势,但它的应用尚未得到广泛报道。
评估一系列使用 Er:YAG 激光治疗光化性唇炎患者的治疗效果。
这是一项回顾性、干预性、非随机、连续病例系列研究,在一家三级转诊皮肤科手术单位进行。2001 年 1 月至 2008 年 6 月期间,99 例光化性唇炎患者接受 Er:YAG 激光治疗,对这些患者进行病历回顾,其中 77 例继续接受结构化电话访谈。主要观察指标为与光化性唇炎相关的唇部症状的主观改善和常规随访时唇部的客观改善。
平均随访至访谈时间为 65.7 个月。接受访谈的患者中,92.2%认为唇部外观有改善;100%认为唇部功能有所改善或保持不变;84.8%在随访时无疾病复发。大多数患者(93.5%)对激光治疗满意。5.1%的患者出现了直接由激光引起的瘢痕。
数据收集的回顾性;无法对所有接受治疗的患者进行访谈。
Er:YAG 激光是治疗光化性唇炎的有效方法,具有良好的功能和美容效果,且长期瘢痕形成的风险较小。它应被视为该疾病的一线治疗方法。