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[大波兰省选定地区(斯特热舒夫镇及乡)的阿尔茨海默病流行病学]

[Epidemiology of Alzheimer's disease in the selected region of Wielkopolska (town and commune Steszew)].

作者信息

Wender M, Mularczyk J, Modestowicz R

机构信息

Katedra Neurologii Akademii Medycznej w Poznaniu.

出版信息

Przegl Epidemiol. 1990;44(3):215-21.

PMID:2084804
Abstract

An epidemiological survey of Alzheimer's disease (senile dementia of Alzheimer type) was conducted on the territory of town and commune Steszew, lying in the Poznań district, with a population of 13,023 on the appointed day, December 31, 1988. Clinical diagnosis was established by detailed anamnesis, neurological, general and psychological examinations. Also a clinical questionnaire containing ischemic scale after Hachinski et al., (1975) was evaluated. The detected overall prevalence rate of Alzheimer's dementia on the appointed day (December 31, 1988) was 1105.7 per 100 thousand population, whereas in the group of persons over 65 years was 10059.2 per 100 thousand. The prevalence rate of severe cases of Alzheimer's disease was established in the group of population over 65 year on 2662.7 per 100 thousand. The detected overall incidence rate of Alzheimer's disease in the year 1988 was in the age class 45-65 years 201.5 per 100 thousand, and in the group over 65 years 2588.8 per 100 thousand. The obtained results of our investigations in the population of western Poland are in the lower part of dispersion of the epidemiologic data on Alzheimer's disease in the world scale. The results indicate that too rarely is diagnosed Alzheimer's disease as a cause of dementia in elderly people, and too often the cerebrovascular disease. The high prevalence rate of demented people in senility indicates on great importance of organization of Inpatients Senior Clinics in which a part of those people shall find a place.

摘要

在波兹南地区的斯特热舒夫镇及公社开展了一项关于阿尔茨海默病(阿尔茨海默型老年痴呆症)的流行病学调查。1988年12月31日指定日期当天,该地人口为13,023人。通过详细的病史采集、神经学、全身及心理学检查进行临床诊断。同时,还对一份包含哈钦斯基等人(1975年)缺血量表的临床问卷进行了评估。1988年12月31日指定日期当天检测到的阿尔茨海默病痴呆症总体患病率为每10万人1105.7例,而65岁以上人群中为每10万人10059.2例。65岁以上人群中阿尔茨海默病重症病例的患病率为每10万人2662.7例。1988年检测到的阿尔茨海默病总体发病率在45 - 65岁年龄组为每10万人201.5例,在65岁以上人群中为每10万人2588.8例。我们在波兰西部人群中的调查结果处于世界范围内阿尔茨海默病流行病学数据分布的较低部分。结果表明,在老年人中,阿尔茨海默病作为痴呆症病因被诊断出的情况太少,而脑血管疾病被诊断出的情况太频繁。老年痴呆症患者的高患病率表明设立老年住院诊所非常重要,这些患者中的一部分应能在其中找到安置之处。

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