Department of Head and Neck Oncology and Surgery, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Head Neck. 2011 Jan;33(1):117-24. doi: 10.1002/hed.21408.
The aim of this study was to assess the heat and moisture exchange (HME) capacity of the upper respiratory tract and the effect of tracheotomy breathing on endotracheal climate in patients with head and neck cancer.
We plotted the subglottic temperature and humidity measurements in 10 patients with head and neck cancer with a temporary precautionary tracheotomy during successive 10-minute periods of nose, mouth, and tracheotomy breathing in a randomized sequence.
End-inspiratory temperatures of nose, mouth, and tracheotomy breathing were 31.1, 31.3, and 28.3°C, respectively. End-inspiratory humidity measurements of nose, mouth, and tracheotomy breathing were 29.3, 28.6, and 21.1 mgH₂O/L, respectively. There was a trend toward lower end-inspiratory humidity in patients with radiotherapy or with large surgery-induced oropharyngeal mucosal defects, whereas temperatures were similar.
This study gives objective information about the HME capacity of the upper respiratory tract in patients with head and neck cancer with precautionary tracheotomy, and thus provides target values for HMEs for laryngectomized and tracheotomized patients.
本研究旨在评估头颈部癌症患者上呼吸道的热湿交换（HME）能力，以及气管切开呼吸对气管内气候的影响。
我们在 10 例头颈部癌症患者中进行了临时预防性气管切开术，随后在连续 10 分钟内随机进行鼻呼吸、口呼吸和气管切开呼吸，绘制了气管隆突下温度和湿度测量值。
鼻呼吸、口呼吸和气管切开呼吸的吸气末温度分别为 31.1°C、31.3°C 和 28.3°C。鼻呼吸、口呼吸和气管切开呼吸的吸气末湿度测量值分别为 29.3mgH₂O/L、28.6mgH₂O/L 和 21.1mgH₂O/L。有放疗或大手术引起的口咽黏膜缺损的患者吸气末湿度有降低的趋势，而温度则相似。
本研究对头颈部癌症预防性气管切开患者的上呼吸道 HME 能力提供了客观信息，从而为喉切除和气管切开患者的 HME 提供了目标值。
