Churches Owen, Wheelwright Sally, Baron-Cohen Simon, Ring Howard
Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, UK.
Neuroreport. 2010 Apr 21;21(6):399-403. doi: 10.1097/wnr.0b013e328334311b.
Face processing deficits are characteristic of autism spectrum conditions. However, event-related potential studies of autism spectrum conditions have found inconsistent results for the face selective N170 component. In this study, 15 adult males with autism spectrum conditions and 15 matched, typically developing controls completed a task in which pictures of faces were either attended to or ignored. In the control group, the N170 was larger when faces were attended to. However, there was no such modulation in the autism spectrum conditions group. This finding helps clarify the results from the earlier event-related potential studies of face processing in autism spectrum conditions and suggests that visual attention does not enhance face processing in autism spectrum conditions as it does in typical development.
面部加工缺陷是自闭症谱系障碍的特征。然而，针对自闭症谱系障碍的事件相关电位研究发现，面部选择性N170成分的结果并不一致。在本研究中，15名患有自闭症谱系障碍的成年男性和15名匹配的发育正常的对照组完成了一项任务，在该任务中，面部图片要么被关注，要么被忽略。在对照组中，当面部被关注时，N170更大。然而，在自闭症谱系障碍组中没有这种调节。这一发现有助于阐明早期关于自闭症谱系障碍面部加工的事件相关电位研究结果，并表明视觉注意力在自闭症谱系障碍中不像在正常发育中那样增强面部加工。
