通过劳斯肉瘤病毒和猿猴病毒40双重转化的人类细胞形成多核巨细胞来检测梅森- Pfizer猴病毒感染。
Detection of Mason-Pfizer monkey virus infection by syncytia formation of human cells doubly transformed by Rous sarcoma virus and simian virus 40.
作者信息
Ogura H, Tanaka T, Ocho M, Kuwata T, Oda T
出版信息
Arch Virol. 1978;57(2):195-8. doi: 10.1007/BF01315682.
PMID:208492
Abstract
Human cells doubly transformed by Rous sarcoma virus and SV40 (RSb cells) formed syncytia by cocultivation with Mason-Pfizer monkey virus (MPMV)-producing cells. This cell fusion was blocked by anti-MPMV serum indicating that the phenomenon is MPMV specific. The RSb cells were successfully used for MPMV infectivity assay in the same manner as KC cells.
摘要
被劳氏肉瘤病毒和SV40双重转化的人类细胞（RSb细胞）与产生梅森 - 辉瑞猴病毒（MPMV）的细胞共培养时形成了多核巨细胞。这种细胞融合被抗MPMV血清阻断，表明该现象具有MPMV特异性。RSb细胞以与KC细胞相同的方式成功用于MPMV感染性测定。
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