Department of Neurological Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
World Neurosurg. 2010 Apr;73(4):395-401. doi: 10.1016/j.wneu.2010.01.024.
Thoracic and lumbar spine surgical procedures are performed for a variety of pathologies. The literature consists of multiple retrospective reviews examining complication prevalence with the surgical treatment of these disorders. However, there is limited direct examination of perioperative complications through a prospective approach. Of the prospective assessments, the majority focuses on specific surgical procedures or provides a limited assessment of certain spinal implants. Prospective assessments of complication incidence in broad patient populations are limited. This article analyzes a prospectively collected database of patients who underwent a thoracic and/or lumbar spine surgery at a large tertiary care center and the effect of surgical approach (anterior or posterior) on the incidence of early complications.
Data collection was performed prospectively on 128 patients on the neurosurgical spine service at Thomas Jefferson University hospital from May to December 2008. Data on preoperative diagnosis, medical comorbidities, body mass index, surgical approach and procedure, length of stay, and complication occurrence was recorded and analyzed. Acute complications or adverse events occurring within the initial 30 days after each operative procedure were included. All medical adverse events were included as complications. A previously circumstantiated binary definition of major and minor complications was used to stratify the data.
Overall, 76 of 128 patients (59.4%) in this cohort experienced at least one complication. Anterior thoracic and lumbar procedures had an 83.3% (5/6) incidence of complications. Of those patients having solely a posterior thoracic and lumbar procedures, 37 of 75 (49.3%) experienced at least one complication. Combined anterior and posterior surgical procedure had a complication incidence of 34 of 47 (72.3%). The mean number of complications reached significance for the minor and overall complications groups (P = .0076 and .0172, respectively, Poisson regression). Comparing the incidence of complications reveals the overall complications in the posterior alone group compared with the anterior/posterior combined group was significantly lower (P = .0134). Those undergoing instrumented fusions were statistically more likely to encounter complications (P < .001).
There is a considerably higher complication incidence than previously reported for thoracic, thoracolumbar, and lumbar spine operations. A prospective approach and a broad definition of perioperative complications increased the recorded incidence of perioperative adverse events and complications. The case complexity of a tertiary referral center may also have escalated the increased incidence. Complications were more common in patients undergoing anterior and anterior/posterior procedures.
胸椎和腰椎手术适用于多种病变。文献中有许多回顾性研究检查了这些疾病的手术治疗中并发症的发生率。然而,通过前瞻性方法直接检查围手术期并发症的研究有限。在这些前瞻性评估中,大多数集中在特定的手术程序上,或者对某些脊柱植入物进行了有限的评估。在广泛的患者群体中,对并发症发生率的前瞻性评估是有限的。本文分析了在一家大型三级保健中心接受胸椎和/或腰椎手术的患者前瞻性收集的数据库,并研究了手术入路(前路或后路)对早期并发症发生率的影响。
2008 年 5 月至 12 月,托马斯杰斐逊大学医院神经外科脊柱服务部前瞻性收集了 128 例患者的数据。记录并分析了术前诊断、合并症、体重指数、手术入路和手术程序、住院时间和并发症发生情况。纳入每种手术术后 30 天内发生的急性并发症或不良事件。所有医疗不良事件均作为并发症纳入。使用先前确定的主要和次要并发症的二元定义来对数据进行分层。
在本队列中,共有 76 例(59.4%)患者至少发生了 1 次并发症。前路胸腰椎手术并发症发生率为 83.3%(5/6)。单纯后路胸腰椎手术患者中,有 37 例(75 例中有 37 例,49.3%)发生了至少 1 次并发症。前路和后路联合手术患者并发症发生率为 34 例(47 例中有 34 例,72.3%)。主要和总并发症组的平均并发症数量具有统计学意义(P=.0076 和.0172,泊松回归)。比较并发症发生率显示,单纯后路组与前路/后路联合组的总体并发症发生率显著较低(P=.0134)。接受器械融合的患者发生并发症的几率显著更高(P <.001)。
与先前报道的胸椎、胸腰椎和腰椎手术相比,该手术的并发症发生率明显更高。前瞻性方法和围手术期并发症的广泛定义增加了围手术期不良事件和并发症的记录发生率。三级转诊中心的病例复杂性也可能导致发生率上升。在前路和前路/后路手术中,并发症更常见。