Shields J A, Shields C L
Ocular Oncology Service, Wills Eye Hospital, Jefferson Medical College, Thomas Jefferson University, Philadelphia PA 19107.
Trans Pa Acad Ophthalmol Otolaryngol. 1990;42:977-80.
The authors report their personal experience and review the pertinent literature on cryotherapy in the treatment of selected patients with retinoblastoma. Tumor destruction with cryotherapy can generally be achieved with one or more treatments if the tumor is no greater than 2.5 mm in diameter and 1.0 mm in thickness and the tumor is confined to the sensory retina without seeding into the adjacent vitreous. Cryotherapy generally fails for larger tumors, particularly if there is clinical evidence of vitreous seeding by tumor cells. The authors define their current indications and contraindications for cryotherapy of retinoblastoma.
作者报告了他们的个人经验，并回顾了有关冷冻疗法治疗特定视网膜母细胞瘤患者的相关文献。如果肿瘤直径不超过2.5毫米、厚度不超过1.0毫米，且肿瘤局限于感觉视网膜而未播散至相邻玻璃体，则通过一次或多次治疗通常可以实现冷冻疗法对肿瘤的破坏。对于较大的肿瘤，冷冻疗法通常会失败，尤其是当有临床证据表明肿瘤细胞播散至玻璃体时。作者明确了他们目前视网膜母细胞瘤冷冻疗法的适应证和禁忌证。
