Department of Pathology, University of Miami Miller School of Medicine/JMH, FL 33136, USA.
Ann Diagn Pathol. 2010 Oct;14(5):358-60. doi: 10.1016/j.anndiagpath.2009.08.005. Epub 2009 Dec 8.
We report a unique case of an extramammary mammary-type myofibroblastoma of the perianal region. The patient was a 40-year old female with no significant past history, who presented with a right side painless perianal mass. Gross examination of the excised mass showed a well-circumscribed, apparently encapsulated, nodular mass weighing 30 g and measuring 5 cm. in the greatest dimension. The cut surface showed solid, yellow homogenous tissue. Microscopically, the neoplasm was composed of bland spindled cells generally arranged into short fascicles with abundant myxoid stroma. The cells stained strongly for desmin and CD34. To our knowledge, a review of the literature discloses only ten cases of extramammary, mammary-type myofibroblastoma.
我们报告了一例独特的肛门周围部位的乳腺外乳腺型肌纤维母细胞瘤病例。患者为 40 岁女性，无明显既往病史，表现为右侧无痛性肛周肿块。切除肿块的大体检查显示，一个边界清楚、明显包膜的结节状肿块，重量为 30 克，最大尺寸为 5 厘米。切面显示为实性、黄色均匀组织。显微镜下，肿瘤由温和的梭形细胞组成，通常排列成短束状，伴有丰富的黏液样基质。细胞强烈表达结蛋白和 CD34。据我们所知，文献复习仅发现 10 例乳腺外乳腺型肌纤维母细胞瘤。
