Yoshida K, Matayoshi K
Department of Obstetrics and Gynecology, Tokyo Medical College, Japan.
Acta Genet Med Gemellol (Roma). 1990;39(3):383-8. doi: 10.1017/s0001566000005316.
It has been suggested that the surviving cotwin and the mother are seriously affected when intrautrine fetal death of one monozygotic twin occurs. Several authors have reported brain damage in the surviving twin coexisting in utero with dead monozygotic cotwin. Most of such instances are monochorionic and show vascular communication between paired twins in the placenta. In a total of 133 pairs of monochorionic twins, death of one twin during pregnancy occurred in 33 cases (24.8%). Of 33 surviving twins, 8 babies suffered from porencephaly, cerebral palsy and other abnormalities. More unfavorable prognosis was recognized when a cotwin died in the latter half of pregnancy, while when a monozygotic cotwin died in the early stage of pregnancy, the surviving twin uneventfully grew to term in most cases.
有人提出,当单卵双胞胎中的一个发生宫内胎儿死亡时,存活的双胞胎和母亲会受到严重影响。几位作者报告了与死亡的单卵双胞胎共存于子宫内的存活双胞胎存在脑损伤。大多数此类情况为单绒毛膜性,且显示胎盘内双胞胎之间存在血管连通。在总共133对单绒毛膜双胞胎中,孕期有一个双胞胎死亡的情况发生了33例(24.8%)。在33名存活的双胞胎中,8名婴儿患有孔洞脑、脑瘫和其他异常。当一个双胞胎在妊娠后半期死亡时,预后更差,而当单卵双胞胎在妊娠早期死亡时,大多数情况下存活的双胞胎能顺利足月出生。