Primavera A, Traverso F
Institute of Clinical Neurology, University of Genova, Italy.
Acta Neurol Belg. 1990;90(5):274-81.
Clinical records and EEGs of 114 consecutive patients with clinical diagnosis of Alzheimer's disease have been reviewed. The EEGs of 15 patients (13%) contained triphasic waves. Triphasic waves were always atypical as they occurred singularly or in short bursts, and/or they had occipital predominance, and/or they were bilateral but asymmetrical. Triphasic waves, in all but one patient were recorded in a state of complete alertness. No statistically significant differences were found between the triphasic waves group and the other one, with respect to age, age at onset, illness duration, presence of seizures. Myoclonus was more frequent in patients with triphasic waves (p less than 0.01). Triphasic waves patients had a higher degree of dementia (p less than 0.01), both in cases with rapidly evolving disease and in subjects with relatively slow clinical course.
对114例临床诊断为阿尔茨海默病的连续患者的临床记录和脑电图进行了回顾。15例患者（13%）的脑电图包含三相波。三相波总是不典型的，因为它们单独出现或呈短阵发放，和/或枕叶优势，和/或双侧但不对称。除1例患者外，所有三相波均在完全清醒状态下记录。三相波组与另一组在年龄、发病年龄、病程、癫痫发作方面未发现统计学显著差异。三相波患者的肌阵挛更频繁（p<0.01）。三相波患者的痴呆程度更高（p<0.01），无论是疾病快速进展的病例还是临床病程相对缓慢的患者。
