Laboratoire de Recherche en Imagerie (LRI), INSERM U970, Equipe N°2, Paris Cardiovascular Research Center - PARCC, 56 rue Leblanc, 75015 Paris, France.
Semin Fetal Neonatal Med. 2011 Feb;16(1):22-8. doi: 10.1016/j.siny.2010.09.001. Epub 2010 Sep 20.
The placenta constitutes a complex circulatory interface between the mother and fetus, but the relationship between the maternal and fetal circulation is still very difficult to study in vivo. There is growing evidence that magnetic resonance imaging (MRI) is useful and safe during pregnancy, and MRI is increasingly used for fetal and placental anatomical imaging. MRI functional imaging is now a modern obstetric tool and has the potential to provide new insights into the physiology of the human placenta. Placental perfusion has been studied during the first pass of an MR contrast agent, by arterial spin labeling, diffusion imaging, T1 and T2 relaxation time measurement using echo-planar imaging, and by a combination of magnetization transfer with established stereological methods. The BOLD (blood oxygen level-dependent) effect offers new perspectives for functional MRI evaluation of the placenta.
胎盘是母体和胎儿之间复杂的循环界面，但在体内研究母体和胎儿循环的关系仍然非常困难。越来越多的证据表明，磁共振成像（MRI）在怀孕期间是有用且安全的，并且 MRI 越来越多地用于胎儿和胎盘的解剖成像。MRI 功能成像现在是一种现代产科工具，有可能为人类胎盘的生理学提供新的见解。已经通过 MRI 对比剂的首过灌注、动脉自旋标记、扩散成像、使用回波平面成像测量 T1 和 T2 弛豫时间以及结合磁化传递与既定的体视学法来研究胎盘灌注。BOLD（血氧水平依赖）效应为胎盘功能 MRI 评估提供了新的视角。
