Department of Neurology, National Institute of Mental Health and Neurosciences, Hosur Road, Bangalore 560029, Karnataka, India.
J Clin Neurosci. 2011 Jan;18(1):138-40. doi: 10.1016/j.jocn.2010.04.047. Epub 2010 Sep 20.
There are few syndromes of parkinsonism with dementia which can be treated. We report two patients with dural arteriovenous fistula (DAVF) who presented with rapidly progressive parkinsonism and cognitive dysfunction. DAVF are rare lesions resulting from abnormal connections between meningeal arteries and dural sinuses. Angiography in both patients revealed DAVF associated with multiple occlusive changes in the dural venous sinus. This report emphasizes the need for a high level of clinical suspicion to diagnose DAVF and consider it as one of the causes of rapidly progressive cognitive dysfunction in patients with parkinsonism.
有一些伴发痴呆的帕金森综合征是可以治疗的。我们报告了两例动静脉瘘(DAVF)患者,他们表现为进行性帕金森病和认知功能障碍。DAVF 是一种罕见的病变,是由于脑膜动脉和硬脑膜窦之间的异常连接引起的。两位患者的血管造影均显示 DAVF 与硬脑膜静脉窦的多处闭塞性改变相关。本报告强调了需要高度的临床怀疑来诊断 DAVF,并将其视为帕金森病患者进行性认知功能障碍的原因之一。