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硬脑膜动静脉瘘所致可逆性帕金森病和快速进展性痴呆:病例系列及文献综述

Reversible Parkinsonism and Rapidly Progressive Dementia Due to Dural Arteriovenous Fistula: Case Series and Literature Review.

作者信息

Lai Joshua, Heran Manraj K S, Stoessl A Jon, Gooderham Peter A

机构信息

Department of Neurology University of British Columbia Vancouver British Columbia Canada.

Department of Radiology University of British Columbia Vancouver British Columbia Canada.

出版信息

Mov Disord Clin Pract. 2017 Mar 27;4(4):607-611. doi: 10.1002/mdc3.12480. eCollection 2017 Jul-Aug.

Abstract

BACKGROUND

Dural arteriovenous fistula (dAVF) rarely presents with a syndrome of reversible parkinsonism and rapidly progressive dementia, which has been described in 19 patients to date. However, its presenting features, pathophysiology, and response to treatment have not been reviewed.

METHODS

We report the clinical course and treatment of two novel patients with this syndrome.

RESULTS

Despite severe presentations, both patients recovered fully after fistula obliteration.

CONCLUSIONS

Atypical parkinsonism with early cognitive changes and other focal neurological signs, along with features such as pulsatile tinnitus or worsening headache, should raise the possibility of dAVF. When treated, this syndrome is nearly always reversible, highlighting the importance of early diagnosis.

摘要

背景

硬脑膜动静脉瘘(dAVF)很少表现为可逆性帕金森综合征和快速进展性痴呆综合征,迄今为止已有19例患者被描述。然而,其临床表现、病理生理学及治疗反应尚未得到综述。

方法

我们报告了两名患有该综合征的新病例的临床过程及治疗情况。

结果

尽管症状严重,但两名患者在瘘管闭塞后均完全康复。

结论

伴有早期认知改变和其他局灶性神经体征的非典型帕金森综合征,以及搏动性耳鸣或头痛加重等特征,应提高dAVF的可能性。经治疗后,该综合征几乎总是可逆的,这凸显了早期诊断的重要性。

相似文献

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Dural arteriovenous fistula-induced thalamic dementia: report of 4 cases.硬脑膜动静脉瘘所致丘脑痴呆:4例报告
J Neurosurg. 2016 Jun;124(6):1752-65. doi: 10.3171/2015.5.JNS15473. Epub 2015 Nov 20.

引用本文的文献

本文引用的文献

1
Dural arteriovenous fistula-induced thalamic dementia: report of 4 cases.硬脑膜动静脉瘘所致丘脑痴呆:4例报告
J Neurosurg. 2016 Jun;124(6):1752-65. doi: 10.3171/2015.5.JNS15473. Epub 2015 Nov 20.

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