Institute of Immunology, Hannover Medical School, Hannover, Germany.
Eur J Immunol. 2010 Aug;40(8):2107-11. doi: 10.1002/eji.201040557.
A specialized network of immune cells is positioned directly in the mucosa of the intestinal tract. In this Viewpoint, we discuss the nature and function of DC and macrophages occupying the intestinal lamina propria of mice. DC and macrophages share phenotypic traits and functional plasticity, properties that preclude simple classification of the two cell types. Nevertheless, the information available appears to have reached "critical mass" to allow for a clear demarcation between intestinal macrophages and DC.
一个专门的免疫细胞网络位于肠道的黏膜中。在这篇观点文章中，我们讨论了定位于小鼠肠固有层的 DC 和巨噬细胞的性质和功能。DC 和巨噬细胞具有表型特征和功能可塑性，这些特性使得难以简单地对这两种细胞类型进行分类。然而，现有的信息似乎已经达到了“临界点”，可以清楚地区分肠道巨噬细胞和 DC。
