Department of Psychology, Virginia Commonwealth University, Richmond, VA 23284, USA.
J Am Acad Child Adolesc Psychiatry. 2010 Oct;49(10):1043-52. doi: 10.1016/j.jaac.2010.06.009. Epub 2010 Jul 31.
Most tests of cognitive behavioral therapy (CBT) for youth anxiety disorders have shown beneficial effects, but these have been efficacy trials with recruited youths treated by researcher-employed therapists. One previous (nonrandomized) trial in community clinics found that CBT did not outperform usual care (UC). The present study used a more stringent effectiveness design to test CBT versus UC in youths referred to community clinics, with all treatment provided by therapists employed in the clinics.
A randomized controlled trial methodology was used. Therapists were randomized to training and supervision in the Coping Cat CBT program or UC. Forty-eight youths (56% girls, 8 to 15 years of age, 38% Caucasian, 33% Latino, 15% African-American) diagnosed with DSM-IV anxiety disorders were randomized to CBT or UC.
At the end of treatment more than half the youths no longer met criteria for their primary anxiety disorder, but the groups did not differ significantly on symptom (e.g., parent report, eta-square = 0.0001; child report, eta-square = 0.09; both differences favoring UC) or diagnostic (CBT, 66.7% without primary diagnosis; UC, 73.7%; odds ratio 0.71) outcomes. No differences were found with regard to outcomes of comorbid conditions, treatment duration, or costs. However, youths receiving CBT used fewer additional services than UC youths (χ(2)(1) = 8.82, p = .006).
CBT did not produce better clinical outcomes than usual community clinic care. This initial test involved a relatively modest sample size; more research is needed to clarify whether there are conditions under which CBT can produce better clinical outcomes than usual clinical care. CLINICAL TRIAL REGISTRY INFORMATION: Community Clinic Test of Youth Anxiety and Depression Study, URL: http://clinicaltrials.gov, unique identifier: NCT01005836.
大多数针对青少年焦虑障碍的认知行为疗法(CBT)测试都显示出有益的效果,但这些都是针对通过研究人员雇佣的治疗师进行治疗的招募青少年进行的疗效试验。以前在社区诊所进行的一项(非随机)试验发现,CBT 并不优于常规护理(UC)。本研究采用更严格的有效性设计,在转诊至社区诊所的青少年中测试 CBT 与 UC 的疗效,所有治疗均由诊所雇佣的治疗师提供。
采用随机对照试验方法。治疗师被随机分配到 Coping Cat CBT 项目或 UC 的培训和监督中。48 名(56%为女孩,8 至 15 岁,38%为白种人,33%为拉丁裔,15%为非裔美国人)被诊断为 DSM-IV 焦虑障碍的青少年被随机分配到 CBT 或 UC。
治疗结束时,超过一半的青少年不再符合其主要焦虑障碍的标准,但两组在症状(例如,父母报告,eta 平方 = 0.0001;儿童报告,eta 平方 = 0.09;两个差异均有利于 UC)或诊断(CBT,66.7%无主要诊断;UC,73.7%;优势比 0.71)结果上没有显著差异。在共病情况、治疗持续时间或成本方面也没有发现差异。然而,接受 CBT 的青少年比接受 UC 的青少年使用的额外服务更少(χ(2)(1) = 8.82,p =.006)。
CBT 并没有比常规社区诊所护理产生更好的临床结果。这项初步测试涉及的样本量相对较小;需要更多的研究来阐明是否存在 CBT 可以产生比常规临床护理更好的临床结果的条件。临床试验注册信息:社区诊所青少年焦虑和抑郁研究,网址:http://clinicaltrials.gov,唯一标识符:NCT01005836。