Khozhiakhmedov G
Biokhimiia. 1990 Nov;55(11):1984-8.
The synthesis of cytoplasmic proteins and the activity of cAMP-dependent protein kinase were studied in the thyroid gland and thymus of intact and irradiated (0.05 Gr) embryos and chicks. The increase in labeled amino acid incorporation into proteins of irradiated chicken endocrine organs during postnatal development was more apparent in thyrocytes. Stimulation of protein kinase activity in the thyroid gland and thymus was observed at the same periods of time. It was supposed that minor doses of ionizing radiation stimulate synthetic processes as well as phosphorylation of proteins responsible for differentiation of avian endocrine organs.
研究了完整和受辐照(0.05戈瑞)胚胎及雏鸡的甲状腺和胸腺中细胞质蛋白的合成以及环磷酸腺苷(cAMP)依赖性蛋白激酶的活性。在出生后发育过程中,受辐照鸡内分泌器官蛋白质中标记氨基酸掺入量的增加在甲状腺细胞中更为明显。在相同时间段观察到甲状腺和胸腺中蛋白激酶活性的刺激。据推测,小剂量电离辐射刺激了禽类内分泌器官分化相关蛋白的合成过程以及磷酸化。