Zonios George, Dimou Aikaterini
Department of Materials Science and Engineering, University of Ioannina, 45110 Ioannina, Greece.
Appl Opt. 2010 Sep 20;49(27):5026-31. doi: 10.1364/AO.49.005026.
A simple two-layer tissue reflectance model is described. This work is a continuation of our investigations on modeling reflectance from two-layered tissues that we recently initiated. In the present article, we describe a variation of a two-layer model that assumes a lower absorbing and scattering layer and an upper scattering-only layer. This two-layer configuration is a realistic model for biological tissues in the visible and near-IR spectral ranges, where the upper layer may be an epithelial layer and the lower layer is a vascularized stroma layer. Application of the model yields estimates for tissue parameters, such as the thickness of the upper layer or the absorption properties of the lower layer. These parameters are of great interest for the noninvasive study of a wide range of epithelial biological tissues. The validity range and accuracy of the model are tested on tissue phantoms in both the forward and inverse modes of application.
本文描述了一种简单的双层组织反射率模型。这项工作是我们最近开始的关于双层组织反射率建模研究的延续。在本文中，我们描述了一种双层模型的变体，该模型假设存在一个低吸收和散射层以及一个仅上层散射层。这种双层结构是可见光和近红外光谱范围内生物组织的现实模型，其中上层可能是上皮层，下层是血管化的基质层。该模型的应用可得出组织参数的估计值，例如上层的厚度或下层的吸收特性。这些参数对于广泛的上皮生物组织的非侵入性研究具有重要意义。该模型的有效范围和准确性在组织模型上以正向和反向应用模式进行了测试。
