Schmitt J M, Knüttel A, Bonner R F
Appl Opt. 1993 Oct 20;32(30):6032-42. doi: 10.1364/AO.32.006032.
We show that optical properties of dense biological tissues can be determined from backscattered power curves measured by a low-coherence reflectometer. Our measurement approach is based on a first-order scattering theory that relates the backscattered power to the total and backscattering cross sections of scatterers in a turbid medium. As a validation of the technique, measurements were made with a commercially available reflectometer on suspensions of polystyrene microspheres having known optical properties. With this reflectometer, which employs a 1300-nm LED source that emits less than 20 µW, we found that skin tissues could be probed to a depth of nearly 1 mm. Estimates of optical coefficients of human dermis and of a variety of excised animal tissues are given.
我们表明，致密生物组织的光学特性可通过低相干反射仪测量的背向散射功率曲线来确定。我们的测量方法基于一阶散射理论，该理论将背向散射功率与混浊介质中散射体的总散射截面和背向散射截面相关联。作为该技术的验证，我们使用市售反射仪对具有已知光学特性的聚苯乙烯微球悬浮液进行了测量。使用这款采用发射功率小于20微瓦的1300纳米发光二极管光源的反射仪，我们发现可以探测到皮肤组织近1毫米的深度。文中给出了人类真皮和多种切除动物组织的光学系数估计值。
