Center on Outcomes, Research and Education, Evanston Northwestern Healthcare, Evanston, IL; Pfizer Global Research and Development, Groton, CT, La Jolla, CA, and New York; Memorial Sloan-Kettering Cancer Center, New York, NY; and Massachusetts General Hospital Cancer Center, Boston, MA.
J Oncol Pract. 2009 Mar;5(2):66-70. doi: 10.1200/JOP.0922004.
In a randomized phase III trial, sunitinib was associated with significantly superior progression-free survival when compared with interferon alfa as first-line therapy in patients with metastatic renal cell carcinoma. This article investigates whether baseline quality of life and demographic and clinical variables were predictive for progression-free survival.
在一项随机 III 期临床试验中,与干扰素 alfa 相比,舒尼替尼作为转移性肾细胞癌的一线治疗药物,显著提高了无进展生存期。本文研究了基线生活质量以及人口统计学和临床变量是否对无进展生存期具有预测价值。