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新型氟代聚硅倍半氧烷中空球:合成及在药物释放中的应用。

Novel fluorinated polysilsesquioxane hollow spheres: synthesis and application in drug release.

机构信息

Department of Polymer Science and Engineering, Pusan National University, Busan, 609-735, Korea.

出版信息

Chem Commun (Camb). 2010 Oct 28;46(40):7498-500. doi: 10.1039/c0cc01658f. Epub 2010 Sep 20.

Abstract

Fluorinated polysilsesquioxane (FPSQ) hollow spheres with a large empty interior were synthesized in an aqueous medium by using (trifluoropropyl)trimethoxysilane as the sole precursor. The drug release applications of these spheres were demonstrated, and the materials have great potential as fluorinated drug release carriers.

摘要

氟代聚硅倍半氧烷(FPSQ)空心球具有较大的内部空腔,在水相中通过使用(三氟丙基)三甲氧基硅烷作为唯一的前驱体制备得到。这些空心球被用于药物释放应用,这些材料作为氟代药物释放载体具有巨大的潜力。

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