Rodríguez González O, Amador García I, Martín Iglesias A, Rodríguez Germa I, Besada Estévez J C
Servicio de Anestesia y Reanimación, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife.
Rev Esp Anestesiol Reanim. 2010 Aug-Sep;57(7):454-7. doi: 10.1016/s0034-9356(10)70272-3.
Pheochromocytomas, which derive from chromaffin cells, can secrete catecholamines in large amounts. The incidence of these tumors is low at 2 to 8 cases per million population and only 10% of cases occur in children. A thorough understanding of the pathophysiology of these tumors and the consequent effect of drugs will be necessary for treating these patients during the perioperative period. A great deal has been published on drugs that can be used in this setting, but only a small portion of the information is relevant to children. Esmolol, a short-action beta-blocker, figures among the drugs that have been developed in recent years. We report a case in which esmolol was used during surgery in a 10-year-old girl undergoing scheduled removal of a bilateral pheochromocytoma.
嗜铬细胞瘤起源于嗜铬细胞，可大量分泌儿茶酚胺。这些肿瘤的发病率较低，每百万人口中为2至8例，仅10%的病例发生在儿童中。在围手术期治疗这些患者时，有必要全面了解这些肿瘤的病理生理学以及药物的相应作用。关于可用于这种情况的药物已经发表了大量文献，但只有一小部分信息与儿童相关。艾司洛尔是一种短效β受体阻滞剂，是近年来开发的药物之一。我们报告了一例在一名计划切除双侧嗜铬细胞瘤的10岁女孩手术期间使用艾司洛尔的病例。
