Shibuya H, Kawashima K, Sakagami M, Kawanishi H, Shimomura M, Ohashi K, Kitagawa I
Faculty of Pharmaceutical Sciences, Osaka University, Japan.
Chem Pharm Bull (Tokyo). 1990 Nov;38(11):2933-8. doi: 10.1248/cpb.38.2933.
Two glycosphingolipids named soya-cerebrosides I and II were isolated from soybean, the seeds of Glycine max Merrill (Leguminosae), and their chemical structures have been elucidated on the basis of physicochemical evidence and several chemical degradation reactions. By using a newly constructed liquid membrane-type apparatus (W-08) for measurement of ion-transport and ion-binding activities and by employing a method using human erythrocyte membranes for measurement of ion-permeability, it has been found that soya-cerebroside II exhibits ionophoretic activity for Ca2+ ion.
从大豆(豆科植物大豆的种子)中分离出了两种名为大豆脑苷脂I和II的糖鞘脂,并根据物理化学证据和一些化学降解反应阐明了它们的化学结构。通过使用新构建的用于测量离子转运和离子结合活性的液膜型装置(W - 08),并采用利用人红细胞膜测量离子渗透性的方法,发现大豆脑苷脂II对Ca2 +离子具有离子载体活性。