Jaiswal S, Agrawal V, Vij M, Sahu R N, Jaiswal A K, Behari S
Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Clin Neuropathol. 2010 Sep-Oct;29(5):330-3. doi: 10.5414/npp29330.
A 54-year-old male presented with the history of headache and vomiting. MRI of the head showed right posterior temporal mass which was surgically excised. Histopathological examination revealed features of glioblastoma with pigmented cells. The pigment was demonstrated to be melanin which was confirmed by special stains and immunohistochemistry. This is the first description of glioblastoma with melanotic differentiation reported in the literature. The relevant literature is briefly reviewed.
一名54岁男性，有头痛和呕吐病史。头部MRI显示右侧颞叶后部有肿块，已手术切除。组织病理学检查显示胶质母细胞瘤伴有色素沉着细胞。经特殊染色和免疫组织化学证实，该色素为黑色素。这是文献中首次报道具有黑色素分化的胶质母细胞瘤。现简要回顾相关文献。
