Luo X Z
Beijing Friendship Hospital.
Zhonghua Wai Ke Za Zhi. 1990 May;28(5):272-3, 317.
Giant-cell tumor of the sacrum is rare. There were only a few reports of large series in the literature. From 1960-1988 a total of ten cases giant-cell tumor of the sacrum were treated in our Department. The average age of the patients was 34 years (with range of 19-49 years). The lesions located in the proximal parts of the sacrums in 8 cases, and in S3-5 in another 2 cases. of 10, 7 were treated with en bloc resection or subtotal resection. of the sacrum, and followed by irradiation in 5 of 7 cases (with range of 2000r-4500r). All the 7 cases were followed up without any evidence of local recurrence or distant metastases. The average follow-up period was 10.3 years (with range of 1.5-27.5 years). The rectal, bladder and sexual function were normal or restored. The other 3 cases, biopsied in 2, partially resected in 1, died less than one year after diagnosis. Comparing the died group with the survival group, we concluded that early diagnosis and thorough excision of the tumor are the two decisive factors for a favorable prognosis.
骶骨巨细胞瘤较为罕见。文献中仅有少数关于大宗病例系列的报道。1960年至1988年,我院共收治10例骶骨巨细胞瘤患者。患者的平均年龄为34岁(年龄范围为19至49岁)。8例病变位于骶骨近端,另2例位于S3 - 5。10例患者中,7例行整块切除或骶骨次全切除,其中7例中的5例术后接受了放射治疗(照射剂量范围为2000r至4500r)。所有7例患者均获随访,无局部复发或远处转移迹象。平均随访时间为10.3年(范围为1.5至27.5年),直肠、膀胱及性功能正常或已恢复。另外3例中,2例行活检,1例行部分切除,均在诊断后不到1年死亡。通过对比死亡组与生存组,我们得出结论:早期诊断及彻底切除肿瘤是预后良好的两个决定性因素。