Huang Z Q
General Hospital of PLA, Beijing.
Zhonghua Wai Ke Za Zhi. 1990 Sep;28(9):522-6, 572.
Carcinoma of the bile duct at the hepatic hilar region is not a rare condition but with a low resectability rate. The incidence of this disease seems to be on increasing. In a previous report, 60 cases were explored surgically from 1975 to 1985, but resection was only possible in 5 cases (9.1%); while in the recent years from June, 1986 to June 1989, 24 cases were explored in the Surgical Department of General Hospital of PLA, 16 cases were resected, with a resectability rate of 66%. The increase of resectability rate was due to earlier recognition of this condition and the extension of surgery, including major resection of liver as well as radical dissection of the hepato-duodenal ligament and reparative operations on the blood vessels. Among these 16 cases, major hepatic resection was performed in 10 cases, in which, 3 cases of resections of the middle lobe of the liver were done instead of right or extended right lobectomy. No operative mortality in the 30 days' postoperative period, but the postoperative morbidity rate was still high and most of the complications were related to biliary leakage and infect ion. Three patients died in the postoperative follow up period at 6.14 and 15 months respectively. All of them died from biliary infection. The remaining 13 patients were still living, the longest being 40 months and the average living time was 16.1 months. Probably, lowering of the operative mortality rate and morbidity rate are still the most important considerations in the surgical treatment of hilar carcinoma at the present time.(ABSTRACT TRUNCATED AT 250 WORDS)
肝门部胆管癌并非罕见疾病,但可切除率较低。该病的发病率似乎呈上升趋势。在之前的一份报告中,1975年至1985年期间对60例患者进行了手术探查,但仅5例(9.1%)可行切除;而近年来,从1986年6月至1989年6月,解放军总医院外科对24例患者进行了探查,16例得以切除,可切除率为66%。可切除率的提高归因于对该疾病的早期诊断以及手术范围的扩大,包括肝大部切除、肝十二指肠韧带根治性清扫以及血管修复手术。在这16例患者中,10例行肝大部切除,其中3例为肝中叶切除而非右叶或扩大右叶切除。术后30天内无手术死亡,但术后发病率仍然较高,且大多数并发症与胆漏和感染有关。3例患者在术后随访期分别于6个月、14个月和15个月死亡。他们均死于胆道感染。其余13例患者仍存活,最长存活时间为40个月,平均存活时间为16.1个月。目前,降低手术死亡率和发病率可能仍是肝门部胆管癌外科治疗中最重要的考量因素。(摘要截选至250词)