晚期卵巢癌的一线化疗：三种治疗方案的比较
Fist line chemotherapy in advanced ovarian cancer: a comparison of three therapeutic regimes.
作者信息
Cherchi P L, Bagella M P, Campiglio A, Rubattu A, Farina M, Ambrosini A
机构信息
Gynaecologic and Obstetric Institute, University of Sassari, Italy.
出版信息
Eur J Gynaecol Oncol. 1990;11(6):453-6.
The first line polichemotherapeutic regimens are compared (intracavitary Cyclophosphamide + CMF, ACy and PEC) in 47 patients with advanced ovarian carcinoma. The response was 56.4% for Ex-CMF (CR 39.1%), 76.8% for ACy (CR 61.5%) and 81.8% for PEC (CR 63.6%). The three-year survival was 39.1% with Ex-CMF, 53.8% with ACy and 72.7% (follow-up not yet completed) for PEC. Toxicity was modest in all the three therapeutic regimens.
对47例晚期卵巢癌患者的一线联合化疗方案（腔内注射环磷酰胺+CMF、ACy和PEC）进行了比较。Ex-CMF方案的缓解率为56.4%（完全缓解率为39.1%），ACy方案为76.8%（完全缓解率为61.5%），PEC方案为81.8%（完全缓解率为63.6%）。Ex-CMF方案的三年生存率为39.1%，ACy方案为53.8%，PEC方案为72.7%（随访尚未完成）。所有三种治疗方案的毒性均较轻。
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