Pindolol inhibits the development of hypoxic pulmonary vasoconstriction.
作者信息
Takashio T, Yamashita H, Onodera S
机构信息
First Department of Internal Medicine, Asahikawa Medical College, Hokkaido, Japan.
出版信息
Eur J Pharmacol. 1990 Dec 4;191(3):493-6. doi: 10.1016/0014-2999(90)94187-3.
PMID:2086253
Abstract
We examined the effects of beta-adrenoceptor antagonists, propranolol and pindolol, on hypoxic pulmonary vasoconstriction using isolated, blood-perfused dog lung lobes. Pindolol markedly inhibited the development of hypoxic pulmonary vasoconstriction, whereas propranolol had no effect. The different role of the drugs on hypoxic pulmonary vasoconstriction is discussed.
摘要
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