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吗啡和丁丙诺啡对离体灌注猫肺及狗肺灌注肺叶中缺氧性肺血管收缩无作用。

Lack of effect of morphine and buprenorphine on hypoxic pulmonary vasoconstriction in the isolated perfused cat lung and the perfused lobe of the dog lung.

作者信息

Gibbs J M, Johnson H

出版信息

Br J Anaesth. 1978 Dec;50(12):1197-201. doi: 10.1093/bja/50.12.1197.

DOI:10.1093/bja/50.12.1197
PMID:747691
Abstract

In an isolated perfused cat lung preparation and a perfused lobe of dog lung preparation a pressor response of the pulmonary circulation was elicited to alveolar hypoxia (5% oxygen). The magnitude of this reponse was not affected by either of the opioid drugs, morphine or buprenorphine.

摘要

在离体灌注猫肺标本和灌注的犬肺叶标本中，肺循环对肺泡低氧（5%氧气）产生了升压反应。这种反应的强度不受阿片类药物吗啡或丁丙诺啡的影响。

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Br J Anaesth. 1978 Dec;50(12):1197-201. doi: 10.1093/bja/50.12.1197.
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