来自黎巴嫩的17个短串联重复序列（STR）标记的群体遗传数据。
Population genetic data for 17 STR markers from Lebanon.
作者信息
Chouery Eliane, Coble Michael D, Strouss Katharine M, Saunier Jessica L, Jalkh Nadine, Medlej-Hashim Myrna, Ayoub Fouad, Mégarbané André
机构信息
Medical Genetics Unit, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.
出版信息
Leg Med (Tokyo). 2010 Nov;12(6):324-6. doi: 10.1016/j.legalmed.2010.08.005. Epub 2010 Sep 21.
Seventeen autosomal STRs were analyzed (D2S1338, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D19S433, D21S11, CSF1PO, FGA, TH01, TPOX, vWA, Penta D, and Penta E) in the Lebanese population. A total of 192 unrelated individuals were genotyped for the 15 autosomal STRs in the Promega PowerPlex 16 STR kit. An additional 275 unrelated individuals were genotyped for the Applied Biosystems AmpFlSTR Identifiler and SGM+STR kits. Allele frequencies for the shared CODIS 13 loci among the three STR kits tested were not significantly different among individuals within the Lebanese population. Forensic and population genetic parameters for the 17 loci were calculated. We also compared the allele frequencies from this population with other populations in the same geographic vicinity.
在黎巴嫩人群中分析了17个常染色体短串联重复序列（D2S1338、D3S1358、D5S818、D7S820、D8S1179、D13S317、D16S539、D18S51、D19S433、D21S11、CSF1PO、FGA、TH01、TPOX、vWA、五聚体D和五聚体E）。总共192名无亲缘关系的个体使用Promega PowerPlex 16 STR试剂盒对15个常染色体短串联重复序列进行了基因分型。另外275名无亲缘关系的个体使用Applied Biosystems AmpFlSTR Identifiler和SGM + STR试剂盒进行了基因分型。在测试的三种STR试剂盒中，黎巴嫩人群个体间共享的CODIS 13个位点的等位基因频率没有显著差异。计算了17个位点的法医学和群体遗传学参数。我们还将该人群的等位基因频率与同一地理区域的其他人群进行了比较。
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