Surgery Department, Medical University of Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Am J Surg. 2010 Nov;200(5):e64-6. doi: 10.1016/j.amjsurg.2010.02.017. Epub 2010 Sep 22.
Historically, tertiary syphilis infection has been the most common cause of thoracic aortic aneurysm, resulting in 5% to 10% of cardiovascular deaths until the era of antibiotics.
A 49-year-old Caucasian man presented to our institution with progressive dysphagia, weight loss, incomplete bladder emptying, alcohol and tobacco consumption, systemic arterial hypertension, Argyll Robertson pupil, leg paresthesias, and mediastinal widening. He was admitted to investigate clinical alterations. Thoracic computed tomography revealed an aortic aneurysm complicated with chronic aortic dissection from the ascending aorta to the iliac vessels with 2 communicating lumens. Cerebrospinal fluid examination tested positive for neurosyphilis in a venereal disease research laboratory test (titre 1/32).
Chronic syphilitic aortic aneurysm complicated with chronic aortic dissection was diagnosed.
This is a unique presentation of a syphilitic infection. Syphilitic aortitis, the hallmark of cardiovascular syphilis, has become rare and is hardly considered by today's clinicians in their differential diagnosis.
historically, tertiary syphilis 感染一直是胸主动脉瘤的最常见病因,在抗生素时代之前导致了 5%至 10%的心血管死亡。
一名 49 岁的白人男性因进行性吞咽困难、体重减轻、不完全排空膀胱、烟酒摄入、全身动脉高血压、Argyll Robertson 瞳孔、下肢感觉异常和纵隔增宽而到我院就诊。他因出现临床改变而入院接受检查。胸部计算机断层扫描显示升主动脉至髂血管的主动脉瘤合并慢性主动脉夹层,有 2 个连通的腔。性病研究实验室试验(滴度 1/32)脑脊液检查显示神经梅毒阳性。
诊断为慢性梅毒性主动脉瘤合并慢性主动脉夹层。
这是一种独特的梅毒感染表现。心血管梅毒的标志性病变——梅毒性主动脉炎已变得罕见,当今的临床医生在鉴别诊断中几乎不再考虑。