Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, USP, CEP, 05508-900 São Paulo, SP, Brazil.
Carbohydr Res. 2010 Nov 2;345(16):2328-33. doi: 10.1016/j.carres.2010.08.019. Epub 2010 Sep 21.
The synthesis of seleno-galactopyranosides in a short and efficient manner is described, starting from the parent carbohydrate d-galactose. The approach described allows the synthesis of small libraries of compounds with a number of structural variations at the group attached to selenium. Compounds with aryl, propargyl, allyl, acyl, and alkyl substituents are described.
本文描述了一种从母体糖 d-半乳糖出发，以短而有效的方式合成硒代半乳糖苷的方法。所描述的方法允许合成具有附着在硒上的基团的数量的结构变化的化合物的小文库。描述了具有芳基、炔丙基、烯丙基、酰基和烷基取代基的化合物。
